发明名称 USE OF PTEN-LONG LEADER SEQUENCE FOR TRANSMEMBRANE DELIVERY OF MOLECULES
摘要 A composition for delivering cargo molecules across biological membranes is provided comprising (i) a peptide comprising consecutive amino acid residues having the sequence set forth in SEQ ID NO 1 for the transport of a cargo molecule across a biological membrane and (ii) the cargo molecule, wherein the cargo molecule is not a peptide comprising amino acid residues having the sequence set forth in SEQ ID NO 4. Methods of delivering cargo molecules across biological membranes are also provided. Methods of treating a tumor, cancer, a metabolic disorder, and a cardiovascular disorder are also provided.
申请公布号 CA2790046(A1) 申请公布日期 2011.08.25
申请号 CA20112790046 申请日期 2011.02.17
申请人 THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 发明人 PARSONS, RAMON
分类号 A61K38/02 主分类号 A61K38/02
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