发明名称 Modulation of Gene Expression by Oligomers Targeted to Chromosomal DNA
摘要 Synthesis of a target transcript of a gene is selectively increased in a mammalian cell by contacting the cell with a polynucleotide oligomer of 12-28 bases complementary to a region within a target promoter of the gene under conditions whereby the oligomer selectively increases synthesis of the target transcript.
申请公布号 US2011207217(A1) 申请公布日期 2011.08.25
申请号 US20100750201 申请日期 2010.03.30
申请人 BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 发明人 COREY DAVID REID;JANOWSKI BETHANY ANN;SHAMES DAVID S.;MINNA JOHN DORRANCE
分类号 C12N5/02 主分类号 C12N5/02
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