发明名称 |
Modulation of Gene Expression by Oligomers Targeted to Chromosomal DNA |
摘要 |
Synthesis of a target transcript of a gene is selectively increased in a mammalian cell by contacting the cell with a polynucleotide oligomer of 12-28 bases complementary to a region within a target promoter of the gene under conditions whereby the oligomer selectively increases synthesis of the target transcript.
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申请公布号 |
US2011207217(A1) |
申请公布日期 |
2011.08.25 |
申请号 |
US20100750201 |
申请日期 |
2010.03.30 |
申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
COREY DAVID REID;JANOWSKI BETHANY ANN;SHAMES DAVID S.;MINNA JOHN DORRANCE |
分类号 |
C12N5/02 |
主分类号 |
C12N5/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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