发明名称 |
IMPROVING ACTIVITY OF FE-S CLUSTER REQUIRING PROTEINS |
摘要 |
The present invention is related to a recombinant host cell, in particular a yeast cell, comprising a dihydroxy-acid dehydratase polypeptide. The invention is also related to a recombinant host cell having increased specific activity of the dihydroxy-acid dehydratase polypeptide as a result of increased expression of the polypeptide, modulation of the Fe-S cluster biosynthesis of the cell, or a combination thereof. The present invention also includes methods of using the host cells, as well as, methods for identifying polypeptides that increase the flux in an Fe-S cluster biosynthesis pathway in a host cell. |
申请公布号 |
WO2011103300(A2) |
申请公布日期 |
2011.08.25 |
申请号 |
WO2011US25258 |
申请日期 |
2011.02.17 |
申请人 |
BUTAMAX(TM) ADVANCED BIOFUELS LLC;FLINT, DENNIS;PAUL, BRIAN JAMES;YE, RICK, W. |
发明人 |
FLINT, DENNIS;PAUL, BRIAN JAMES;YE, RICK, W. |
分类号 |
C12N1/19;C12N15/52;C12P7/16;G01N33/68 |
主分类号 |
C12N1/19 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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