发明名称 |
Ply-GBS mutant lysins |
摘要 |
Methods, compositions and articles of manufacture useful for the treatment of various Group B streptococci (GBS) bacteria are provided. Various bacterial lysins, including certain PlyGBS mutant lysins, are provided. In particular, PlyGBS mutant lysins having lytic killing activity against Group B streptococci (GBS) bacteria are provided, including PlyGBS mutant lysins with greater killing activity against Group B streptococci (GBS) bacteria than the non-mutated PlyGBS bacterial lysin.
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申请公布号 |
EP2360248(A1) |
申请公布日期 |
2011.08.24 |
申请号 |
EP20100191784 |
申请日期 |
2006.08.17 |
申请人 |
THE ROCKEFELLER UNIVERSITY |
发明人 |
FISCHETTI, VINCENT, A;CHENG, QI |
分类号 |
C07K14/01;C12N9/78;A61K38/00;C07K14/005;C12N9/80 |
主分类号 |
C07K14/01 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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