Collagen producing plants and methods of generating and using same

摘要

The present invention concerns a recombinant collagen, having been produced in a plant or isolated plant cells generated by targeting at least one type of a collagen chain and an exogenous mammalian prolyl 4 hydroxylase (P4H) to a vacuole of the plant or the isolated plant cells so as to allow hydroxylation of said at least one type of said collagen chain by said P4H and not by an endogenous P4H of the plant or isolated plant cells.