发明名称 |
DNA vaccine compositions and methods of use |
摘要 |
The present invention is directed to a DNA vaccine for immunization against HIV. The invention comprises a DNA molecule that has a sequence encoding a plurality of viral proteins capable of stimulating an immune response against HIV. The DNA molecule is rendered safe for used as a vaccine by the disruption of genes encoding reverse transcriptase, integrase, and Vif. The DNA molecule is further rendered safe by at least a partial deletion of the 3′ LTR.
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申请公布号 |
US8003113(B2) |
申请公布日期 |
2011.08.23 |
申请号 |
US20090368151 |
申请日期 |
2009.02.09 |
申请人 |
NARAYAN OPENDRA;LIU ZHENQIAN |
发明人 |
NARAYAN OPENDRA;LIU ZHENQIAN |
分类号 |
A61K39/21;A01N43/04;A01N63/00;A61K;A61K39/12;A61K48/00;C07H21/04;C12N15/00;C12N15/63;C12N15/86 |
主分类号 |
A61K39/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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