发明名称 Purification of vaccinia virus- and recombinant vaccinia virus-based vaccines
摘要 The present invention relates to methods for purification of Vaccinia viruses (VV) and/or Vaccinia virus (VV) particles, which can lead to highly pure and stable virus preparations of predominantly biologically active viruses. The invention encompasses purifying a virus preparation in a sterilized way with high efficiency and desirable yield in terms of purity, biological activity and stability, aspects advantageous for industrial production.
申请公布号 US8003363(B2) 申请公布日期 2011.08.23
申请号 US20090622474 申请日期 2009.11.20
申请人 BAVARIAN NORDIC A/S 发明人 DJURUP RENE;POST HANSEN SARA
分类号 C12N7/02;A61K39/285 主分类号 C12N7/02
代理机构 代理人
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