发明名称 |
Chemical synthesis of a highly potent epothilone |
摘要 |
A highly active synthetic epothilone compound whose activity exceeds that of either epothilone EpoA or EpoB when assayed as a cytotoxic agent against a cancer cell line is disclosed as is a pharmaceutical composition containing the synthetic epothilone.
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申请公布号 |
US8003801(B2) |
申请公布日期 |
2011.08.23 |
申请号 |
US20060092038 |
申请日期 |
2006.11.09 |
申请人 |
THE SCRIPPS RESEARCH INSTITUTE |
发明人 |
NICOLAOU KYRIACOS C.;PRATT BENJAMIN;ARSENIYADIS STELLIOS |
分类号 |
C07D277/04;C07D231/00;C07D233/00;C07D249/08;C07D257/04;C07D277/60 |
主分类号 |
C07D277/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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