发明名称 Thiophene derivatives as S1P1/EDG1 receptor agonists
摘要 The invention relates to thiophene derivatives of formula (I)/their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents wherein: A represents *—CO—CH═CH—, *—CO—CH2CH2—, *—CO—CH2—NH—, wherein the asterisks indicate the bond that is linked to the thiophene group of Formula (I), and R1-R3 are as defined in the claims.
申请公布号 US8003800(B2) 申请公布日期 2011.08.23
申请号 US20070160520 申请日期 2007.01.10
申请人 ACTELION PHARMACEUTICALS LTD. 发明人 BOLLI MARTIN;LEHMANN DAVID;MATHYS BORIS;MUELLER CLAUS;NAYLER OLIVER;STEINER BEAT;VELKER JOERG
分类号 C07D271/06 主分类号 C07D271/06
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