发明名称 Crystal of hydroxynorephedrin derivative hydrochloride ¼ hydrate
摘要 The present invention provides ethyl (−)-2-[4-[2-[[1S,2R]-2-hydroxy-2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]-2,5-dimethylphenoxyacetate hydrochloride ¼ hydrate or a crystal thereof which can be determined by characteristic diffraction peaks of the powder X-ray diffraction, thermogravimetry-differential thermal analysis or the like, and obtained by manufacturing ethyl (−)-2-[4-[2-[[1S,2R]-2-hydroxy-2-(4-hydroxyphenyl)-1-methyl-ethyl]amino]ethyl]-2,5-dimethylphenoxyacetate by a specific method.
申请公布号 US8003694(B2) 申请公布日期 2011.08.23
申请号 US20060912420 申请日期 2006.04.24
申请人 KISSEI PHARMACEUTICAL CO., LTD. 发明人 ISAWA HIDETOSHI;TODA MICHIO
分类号 A61K31/24;C07C229/38 主分类号 A61K31/24
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