| 摘要 |
FIELD: medicine. ^ SUBSTANCE: what is offered is a modified botulinum toxin containing a natural heavy chain and a modified light chain. What is described is using the modified botulinum toxin for preparing a drug for treating dystonia, and also for eliminating face wrinkles. Nucleic acid coding the modified botulinum toxin is presented. Also, a vector containing nucleic acid, and a host cell containing the vector are also presented. ^ EFFECT: higher stability and prolonged therapeutic action. ^ 22 cl, 2 dwg, 4 tbl, 8 ex |
