| 摘要 |
FIELD: medicine. ^ SUBSTANCE: group of inventions relates to medicine, namely to oncology and can be used in treatment of drug-resistant cancer. Method and composition by the invention include introduction with formula I compound to patient with cancer who has drug-resistant cancer and cytoplasmic tyrosine kinase or receptor tyrosine kinase, Which includes mutant residue "ÇÇé". ^ EFFECT: application of inventions makes it possible to treat drug-resistant cancer by inhibiting mutant kinases with formula I compound. ^ 43 cl, 8 tbl, 26 dwg |
