发明名称 |
METHOD FOR PRODUCING GLYCOPROTEIN CHARACTERIZED BY SUGAR CHAIN STRUCTURE BY USING SILKWORM |
摘要 |
It is an object of the present invention to investigate what kinds of structures a sugar chain has by performing a sugar chain structural analysis of a glycoprotein produced in a transgenic silkworm. For the sugar chain of the glycoprotein produced in the transgenic silkworm, a glycoprotein having a sugar chain structure in which fucose is not linked to N-acetylglucosamine at a reducing terminal of the sugar chain is obtained. In addition, a glycoprotein having an almost completely humanized sugar chain structure is obtained by further integrating GalT gene into this transgenic silkworm.
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申请公布号 |
US2011203009(A1) |
申请公布日期 |
2011.08.18 |
申请号 |
US20090997333 |
申请日期 |
2009.06.15 |
申请人 |
TOMITA MASAHIRO;NAKAKITA SHINICHI;HIRABAYASHI JUN |
发明人 |
TOMITA MASAHIRO;NAKAKITA SHINICHI;HIRABAYASHI JUN |
分类号 |
C12P21/00;A01K67/033;C07H21/04;C12N5/10 |
主分类号 |
C12P21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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