发明名称 |
METHOD FOR MANUFACTURING SUSTAINED RELEASE MICROSPHERE BY SOLVENT FLOW EVAPORATION METHOD |
摘要 |
The present invention relates to a method for preparing a sustained-release microsphere which can control the long-term release of a drug. More particularly, as the preparation of a microsphere in which a drug is loaded in a carrier comprising a biodegradable polymer, the present invention relates to a method for preparing a sustained-release microsphere wherein a solvent intra-exchange evaporation method by means of co-solvent is used for suppressing the initial burst release of physiologically active substance, to release the physiologically active substance in the body continuously and uniformly.
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申请公布号 |
US2011200679(A1) |
申请公布日期 |
2011.08.18 |
申请号 |
US200913061389 |
申请日期 |
2009.08.28 |
申请人 |
DONGKOOK PHARMACEUTICAL CO., LTD. |
发明人 |
LIM NAK HYUN;KIM SUNG GEUN;KIM SE YEON;JUNG HYUNG JOON;CHA KYUNG HOI |
分类号 |
A61K9/14;A61K38/09;A61P5/24 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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