| 摘要 |
Disclosed are methods for screening therapeutics, prophylactics or pain alleviators for diseases induced by TNF-α, a main mediator of inflammation and in ROS production and cell death, and for diagnosing the diseases, and a diagnostic kit. For this, a nucleotide sequence and an amino acid sequence of Romo1, which plays an important role in the ROS production and cell death pathway of TNF-α signaling are utilized.
|
