发明名称 |
SMART POLYMERS FUNCTIONALIZED HOLLOW SILICA VESICLES |
摘要 |
The present invention provides a porous hollow silica micro- or nanoparticle with a polymer grafted thereon, wherein the polymer is selected from poly(methacrylic acid) and copolymers thereof. The polymer may be covalently linked to the silica particle via a bridging group. Provided is also a method of covalently coupling a poly(methacrylic acid) to a silica surface of a hollow silica particle. The method comprises contacting a silica surface of a hollow silica particle that carries amino functional or halogen functional groups with a poly(methacrylic acid) or a copolymer or a respective monomer thereof. The method further comprises allowing the carboxyl group of the monomer or the poly(methacrylic acid) and an amino functional group or a halogen functional group on the silica surface to undergo a coupling reaction, thereby covalently coupling the polymer to the silica surface. |
申请公布号 |
WO2011099932(A1) |
申请公布日期 |
2011.08.18 |
申请号 |
WO2010SG00043 |
申请日期 |
2010.02.09 |
申请人 |
AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH;LIU, YE;LAY, CHEE LENG |
发明人 |
LIU, YE;LAY, CHEE LENG |
分类号 |
C01B33/18;A61K9/52;B82B3/00;C08F20/06 |
主分类号 |
C01B33/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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