发明名称 HETEROARYL SUBSTITUTED PIPERIDINES
摘要 The invention relates to compounds of formula where hetaryl I, hetaryl II, R1, R2, R3, R4, m, n, and o are as defined in the specification or to pharmaceutically active acid addition salts thereof. The compounds of formula I are modulators for amyloid beta and thus may be useful for the treatment or prevention of a disease associated with the deposition of &bgr;-amyloid in the brain, in particular Alzheimer's disease, and other diseases such as cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, Dutch-type (HCHWA-D), multi-infarct dementia, dementia pugilistica and Down syndrome.
申请公布号 US2011201605(A1) 申请公布日期 2011.08.18
申请号 US201113023563 申请日期 2011.02.09
申请人 BAUMANN KARLHEINZ;FLOHR ALEXANDER;GOETSCHI ERWIN;GREEN LUKE;JOLIDON SYNESE;KNUST HENNER;LIMBERG ANJA;LUEBBERS THOMAS;THOMAS ANDREW 发明人 BAUMANN KARLHEINZ;FLOHR ALEXANDER;GOETSCHI ERWIN;GREEN LUKE;JOLIDON SYNESE;KNUST HENNER;LIMBERG ANJA;LUEBBERS THOMAS;THOMAS ANDREW
分类号 A61K31/5365;A61K31/437;A61K31/454;A61K31/506;A61K31/5377;A61P25/28;C07D401/14;C07D403/14;C07D413/14;C07D471/04;C07D498/04 主分类号 A61K31/5365
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