发明名称
摘要 A method for changing a globular protein structure into a fibrillar protein structure. The method comprising the steps of providing a globular protein, forming a solution containing the globular protein, adding a detergent to the solution containing the globular protein, applying the solution to a molecular sizing column with a pore size of at least 70 kDa and eluting with a solution containing detergent. A method for changing an unfolded protein structure into a fibrillar protein structure. The method comprising the steps of providing a globular protein, forming a solution containing the globular protein, adding a urea to the solution to unfold the globular protein, applying the solution to a molecular sizing column and eluting with a solution containing detergent. A method for treating cancer comprising the steps of providing a protein, changing the protein into a fibrillar structure, and administering a therapeutically effective amount of the fibrillar structure protein to a patient in need thereof. A method for producing a vaccine adjuvant or antigen adjuvant comprising the steps of providing a protein, and changing the protein into a fibrillar structure.
申请公布号 JP2011523623(A) 申请公布日期 2011.08.18
申请号 JP20100550909 申请日期 2009.03.13
申请人 发明人
分类号 C07K1/113;A61K35/76;A61K38/00;A61K38/16;A61K39/00;A61K39/39;A61P35/00;A61P37/04;C07K1/16;C12N15/09 主分类号 C07K1/113
代理机构 代理人
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