发明名称 |
PREPARATION OF BENZOFURANS AND USE THEREOF AS SYNTHETIC INTERMEDIATES |
摘要 |
<p>The present invention provides several synthetic methods for preparing N-(2-butylbenzofuran-5-yl)-N-(methylsulfonyl)methanesulfonamide, a compound of formula (3), an intermediate in the preparation of Dronedarone. The present invention further provides a process for preparing Dronedarone, comprising the steps of converting 2-butyl-5-bis(methanesulfon)-amidobenzofuran of formula (3) to Dronedarone, wherein the 2-butyl-5-bis(methanesulfon)-amidobenzofuran of formula (3) is prepared by the processes of the present invention.</p> |
申请公布号 |
WO2011099010(A1) |
申请公布日期 |
2011.08.18 |
申请号 |
WO2011IL00150 |
申请日期 |
2011.02.10 |
申请人 |
MAPI PHARMA HOLDINGS (CYPRUS) LIMITED;MAROM, EHUD;MIZHIRITSKII, MICHAEL;RUBNOV, SHAI |
发明人 |
MAROM, EHUD;MIZHIRITSKII, MICHAEL;RUBNOV, SHAI |
分类号 |
A01N43/08 |
主分类号 |
A01N43/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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