<p>The present invention is directed to improved compositions for cellular delivery of peptides. Using segments of only 3-5 positively-charged residues, one can effectively transfer peptides, including therapeutic peptides, into cells. Also provided are modified peptides such as those include stapled and cyclized peptide technology, as well as peptoids/peptidomimetics.</p>
申请公布号
WO2011100688(A1)
申请公布日期
2011.08.18
申请号
WO2011US24760
申请日期
2011.02.14
申请人
DANA-FARBER CANCER INSTITUTE, INC.;GENUS ONCOLOGY, LLC;KUFE, DONALD, W.;KHARBANDA, SURENDER