发明名称 |
PROCESS FOR THE MANUFACTURE OF AN INDOLINONE DERIVATIVE |
摘要 |
The present invention relates to a process for the manufacture of a specific indolinone derivative and a pharmaceutically acceptable salt thereof, namely 3-Z-[1-(4-(N-((4-methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)-anilino)-1-phenyl-methylene]-6-methoxycarbonyl-2-indolinone and its monoethanesulfonate, to new manufacturing steps and to new intermediates of this process.
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申请公布号 |
US2011201812(A1) |
申请公布日期 |
2011.08.18 |
申请号 |
US20080745796 |
申请日期 |
2008.12.02 |
申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH |
发明人 |
MERTEN JOERN;LINZ GUENTER;SCHNAUBELT JUEGEN;SCHMID ROLF;RALL WERNER;RENNER SVENJA;REICHEL CARSTEN;SCHIFFERS ROBERT |
分类号 |
C07D403/12 |
主分类号 |
C07D403/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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