发明名称 |
EXTENDED RELEASE PREPARATION |
摘要 |
<p>Disclosed is an extended release preparation which releases a poorly soluble medicinal agent in a pH-independent manner. Also disclosed is an extended release preparation which is capable of controlling the Cmax of a medicinal agent to an adequate amount and is thus capable of maintaining the level of the medicinal agent in the blood to a level at which medicinal effects can be expected for a long period of time. Specifically disclosed is an extended release preparation which is characterized by containing a pharmaceutically acceptable salt of 4-bromo-6-[3-(4-chlorophenyl)propoxy]-5-(3- pyridylmethylamino)-3(2H)-pyridazinone, and hypromellose. An organic acid is blended in the extended release preparation in an amount of less than 1% by mass.</p> |
申请公布号 |
WO2011099573(A1) |
申请公布日期 |
2011.08.18 |
申请号 |
WO2011JP52909 |
申请日期 |
2011.02.10 |
申请人 |
TAISHO PHARMACEUTICAL CO., LTD.;NISSAN CHEMICAL INDUSTRIES, LTD.;HIRASAWA NORIYUKI;KAMIKIDO NOBUYOSHI;TASAKI AKIHIKO;ITO SHUSEI |
发明人 |
HIRASAWA NORIYUKI;KAMIKIDO NOBUYOSHI;TASAKI AKIHIKO;ITO SHUSEI |
分类号 |
A61K31/513;A61K47/32;A61K47/38;A61P11/06 |
主分类号 |
A61K31/513 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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