发明名称 |
AGONIST DR5 BINDING POLYPEPTIDES |
摘要 |
<p>The present invention relates to amino acid sequences that are directed against TRAIL cell surface receptor 2 (herein also "DR5"), as well as to compounds or constructs thereof, and in particular proteins and polypeptides and nucleotides that encode them (referred to herein in their entirety as "NB agents") and fragments thereof, and pharmaceutically effective variants thereof, and their use in the diagnosis and treatment of DR5 associated diseases and disorders.</p> |
申请公布号 |
CA2789251(A1) |
申请公布日期 |
2011.08.18 |
申请号 |
CA20112789251 |
申请日期 |
2011.02.10 |
申请人 |
NOVARTIS AG;ABLYNX NV |
发明人 |
CROMIE, KAREN;DOMBRECHT, BRUNO;ETTENBERG, SETH;KOLKMAN, JOOST;LI, JING;MEERSCHAERT, KRIS;STOVER, DAVID RAYMOND;ZHANG, JINGXIN |
分类号 |
C07K16/28;A61K39/395 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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