| 摘要 |
Biocompatible, lubricious, highly durable coatings for medical devices are formed from a highly adherent base-coat and a hydrophilic top-coat that is chemically grafted to the base-coat and has a chemically cross-linked structure. The base-coat constitutes a carboxylic acid containing polymer. The top-coat includes a carboxylic acid containing hydrophilic polymer and chromium (III) ion as the cross-linking agent. The coating possesses biocompatibility and gamma ray-sterilization stability. The coated products in aqueous media display an unmatched combination of lubricity, abrasion resistance, and chemical stability.
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