发明名称 |
TARGETED GENOMIC MODIFICATION WITH PARTIALLY SINGLE-STRANDED DONOR MOLECULES |
摘要 |
Disclosed herein are donor molecules comprising single-stranded complementary regions flanking one or more sequences of interest. The donor molecules and/or compositions comprising these molecules can be used in methods for targeted integration of an exogenous sequence into a specified region of interest in the genome of a cell. |
申请公布号 |
CA2788850(A1) |
申请公布日期 |
2011.08.18 |
申请号 |
CA20112788850 |
申请日期 |
2011.02.09 |
申请人 |
SANGAMO BIOSCIENCES, INC. |
发明人 |
COST, GREGORY J.;GUSCHIN, DMITRY Y.;URNOV, FYODOR |
分类号 |
C12N15/11;C07H21/00;C12N15/90;C12P19/34 |
主分类号 |
C12N15/11 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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