发明名称 N-[3-fluoro-4-({6-(methyloxy)-7-[(3-morpholin-4-ylpropyl)oxy]quinolin-4-yl}oxy)phenyl]-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide for the treatment of cancer
摘要 The present invention provides a compound which is represented by the following structure: which inhibits, regulates and/or modulates kinase receptors, particularly c-Met, KDR, c-Kit, flt-3 and flt-4. This compound is therefore suitable for the treatment of diseases or disorders associated with uncontrolled, abnormal and/or unwanted cellular activities.
申请公布号 EP2210607(B1) 申请公布日期 2011.08.17
申请号 EP20100160517 申请日期 2004.09.24
申请人 EXELIXIS, INC. 发明人 BANNEN, LYNNE CANNE;CHAN, DIVA SZE-MING;CHEN, JEFF;DALRYMPLE, LISA ESTHER;FORSYTH, TIMOTHY PATRICK;HUYNH, TAI PHAT;JAMMALAMADAKA, VASU;KHOURY, RICHARD GEORGE;LEAHY, JAMES WILLIAM;MAC, MORRISON B.;MANN, GRACE;MANN, LARRY W.;NUSS, JOHN M.;PARKS, JASON JEVIOUS;TAKEUCHI, CRAIG STACY;WANG, YONG;XU, WEI
分类号 A61K31/47;A61K;A61K31/535;A61P35/00;C07D215/16;C07D215/20;C07D215/22;C07D413/00 主分类号 A61K31/47
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