发明名称 |
METHOD AND KIT FOR DETECTING BIOLOGICAL SIGNAL OF THREE-DIMENSIONAL CELL CULTURE MATERIAL |
摘要 |
Disclosed is a method for detecting a biological signal of a three-dimensional cell culture construct. The method for detecting a biological signal of a three-dimensional cell culture construct includes: providing a three-dimensional cell culture construct that contains at least two cell layers laminated to each other and a sensor particle capable of detecting a biological signal; and observing the sensor particle optically. Preferably, the three-dimensional cell culture construct contains an extracellular matrix including a combination of a protein or polymer having an RGD sequence and a protein or polymer that interacts with the protein or polymer having the RGD sequence, or a combination of a protein or polymer that is positively charged and a protein or polymer that is negatively charged. |
申请公布号 |
EP2357251(A1) |
申请公布日期 |
2011.08.17 |
申请号 |
EP20090826077 |
申请日期 |
2009.11.10 |
申请人 |
JAPAN SCIENCE AND TECHNOLOGY AGENCY |
发明人 |
MATSUSAKI,MICHIYA;AKASHI, MITSURU;OKANO, KAZUNORI |
分类号 |
C12Q1/02 |
主分类号 |
C12Q1/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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