COMPOSITION FOR PREVENTING OR TREATING IMMUNE DISEASE COMPRISING GRIM19 AS AN ACTIVE INGREDIENT

摘要

PURPOSE: A composition containing Grim19 for preventing or treating immune diseases is provided to suppress cytotoxic Th17 cell differentiation and to activate regulatory T cells. CONSTITUTION: A composition for preventing or treating immune diseases contains Grim19 protein as an active ingredient. The Grim19 protein has an amino acid sequence of sequence number 1. The immune diseases are autoimmune diseases, inflammatory diseases, and transplantation rejection diseases of cells, tissues, or organs. A method for activating regulatory T cells comprises a step of treating Grim 19 protein or an expression vector to the T cells. The expression vector contains a polynucleotide encoding Grim19 protein.