| 发明名称 |
SYSTEMIC DELIVERY OF SERUM STABLE PLASMID LIPID PARTICLES FOR CANCER THERAPY |
| 摘要 |
The present invention relates to methods and compositions for treating a neoplasia in a mammal with a therapeutic nucleic acid, such as a plasmid encoding an expressible gene, wherein the therapeutic nucleic acid is encapsulated in a lipid particle and administered at a site distal to the site of neoplasia, preferably intravenously, and delivered to the site of neoplasia by systemic delivery.
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| 申请公布号 |
CA2321837(C) |
申请公布日期 |
2011.08.16 |
| 申请号 |
CA19992321837 |
申请日期 |
1999.02.03 |
| 申请人 |
INEX PHARMACEUTICALS CORPORATION |
发明人 |
MACLACHLAN, IAN;GRAHAM, ROGER |
| 分类号 |
A61K9/14;A61K48/00;A61K31/711;A61K38/20;A61K38/45;A61K38/51;A61K45/00;A61K47/44;A61P35/00;C12N15/88 |
主分类号 |
A61K9/14 |
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