发明名称 |
Compounds that bind to p185 and methods of using the same |
摘要 |
Novel peptides and pharmaceutical compositions comprising the same are disclosed. Conjugated compositions peptides linked to detectable agents and/or cytotoxic agents are disclosed. Method of detecting tumors that have p185 on tumor cell surfaces are disclosed. Methods of preventing transformation of a normal cell into a tumor cell in an individual at risk of developing a tumor having tumor cells which have p185 on their surfaces are disclosed. Methods of treating an individual who has cancer characterized by tumor cells that have a p185 on their cell surfaces are disclosed.
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申请公布号 |
US7998924(B2) |
申请公布日期 |
2011.08.16 |
申请号 |
US20100758435 |
申请日期 |
2010.04.12 |
申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA |
发明人 |
GREENE MARK I.;MURALI RAMACHANDRAN;BEREZOV ALAN |
分类号 |
A61K38/00;A61K38/04;A61K51/00;C07K5/00;C07K7/00;C07K16/00;C07K16/32;C07K17/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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