发明名称 |
Early detection of pathogens in blood |
摘要 |
The present invention is a method of extracting infectious pathogens from a volume of blood including the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The fibrin lysis reagent is preferably composed of plasminogen and streptokinase frozen in coincident relation until the fibrin lysis reagent is needed whereby streptokinase enzymatically reacts with plasminogen to form plasmin upon thawing. The plasminogen is suspended in an aqueous salt solution prior to freezing including NaCl and Na3PO4.
|
申请公布号 |
US7998699(B2) |
申请公布日期 |
2011.08.16 |
申请号 |
US20030604779 |
申请日期 |
2003.08.15 |
申请人 |
UNIVERSITY OF SOUTH FLORIDA |
发明人 |
EWERT MATT;AMUSO PHILIP;CANNONS ANDREW |
分类号 |
C12Q1/68;C12Q1/02;C12Q1/04;C12Q1/54;C12Q1/56;G01N33/86 |
主分类号 |
C12Q1/68 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|