| 发明名称 |
MODIFIED OLIGONUCLEOTIDES FOR TELOMERASE INHIBITION |
| 摘要 |
Compounds comprising an oligonucleotide moiety covalently linked to a lipid moiety are disclosed. The oligonucleotide moiety comprises a sequence that is complementary to the RNA component of human telomerase. The compounds inhibit telomerase activity in cells with a high potency and have superior cellular uptake characteristics. |
| 申请公布号 |
KR20110091825(A) |
申请公布日期 |
2011.08.12 |
| 申请号 |
KR20117017803 |
申请日期 |
2004.09.09 |
| 申请人 |
GERON CORPORATION |
发明人 |
GRYANOV SERGEI;PONGRACZ KRISZTINA |
| 分类号 |
C12N15/113;A01N43/04;A61K31/7088;A61K48/00;A61P35/00;C07H21/02;C07H21/04;C12N;C12N5/00 |
主分类号 |
C12N15/113 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
