COMPOSITION FOR DIAGNOSING SUSCEPTIBILITY TO CANCER COMPRISING ANTI-TMAP/CKAP2 ANTIBODY

摘要

PURPOSE: An antibody which specifically binds to TMAP(Tumor associated microtubule associated protein)/CKAP2(cytoskeleton associated protein 2) is provided to identify cell division cycle and to diagnose cancer. CONSTITUTION: A composition for diagnosing cancer prognosis contains anti-TMAP/CKAP2 antibody or epitope thereof. The composition is used for measuring mitosis of cells. The cancer is breast cancer or gastrointestinal stromal tumor(GIST). A kit for diagnosing cancer predict contains anti-TMAP/CKAP2 antibody or epitope. The kit is used for predicting disease-free survival rate or survival rate. A method for providing information for diagnosing cancer comprises: a step of treating anti-TMAP/CKAP2 or epitope to a sample isolated from a test individual; a step of comparing antibody-antigen reaction level; and a step of determining cancer with bad prognosis in case of high antibody-antigen reaction level.