EXPRESSION VECTOR HAVING MULTIPLE COPY OF TARGET PROTEIN GENE FOR ESTABLISHING HYPER-PRODUCING CELL

摘要

PROBLEM TO BE SOLVED: To provide an expression vector that is effective for efficiently establishing a transformed cell expressing a target protein gene in a high level.

SOLUTION: The expression vector includes a multiple copy composed of a target protein gene expression cassette, a gene expression stabilizing element and/or an expression cassette for a drug selection marker gene, which comprises an mRNA-destabilizing sequence.

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