发明名称 Methods of identifying responders to dopamine agonist therapy
摘要 The present invention is directed to a method of identifying patients to be treated by dopamine agonist therapy comprising the step of analyzing a plasma or urine sample from said patient for concentrations of norepinephrine (NE), norepinephrine metabolites (NE metabolites), dopamine, dopamine metabolites, serotonin, serotonin metabolites, or fasting triglycerides, wherein one or more of: (a) NE metabolites, (b) NE/NE metabolites: dopamine/dopamine metabolites, (c) NE and serotonin, (d) NE/NE metabolites and serotonin, (e) NE and serotonin metabolites, (f) NE/NE metabolites and serotonin metabolites, or (g) NE is/are greater than about 30% over normal level; or dopamine/dopamine metabolites are less than about 30% below normal; or said patient has hypertriglyceridemai and/or hypertension . The present invention is also directed to treating identified patients with dopamine agonist therapy.
申请公布号 US2011195971(A1) 申请公布日期 2011.08.11
申请号 US201113066280 申请日期 2011.04.11
申请人 CINCOTTA ANTHONY H 发明人 CINCOTTA ANTHONY H.
分类号 A61K31/4985;A61P3/00;A61P3/04;A61P3/06;A61P3/08;A61P3/10;A61P9/00;G01N30/02 主分类号 A61K31/4985
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