发明名称 |
CONTROLLED TUNNEL GAP DEVICE FOR SEQUENCING POLYMERS |
摘要 |
The invention includes compositions, devices, and methods for analyzing a polymer and/or polymer unit. The polymer may be a homo- or hetero-polymer such as DNA, RNA, a polysaccharide, or a peptide. The device includes electrodes that form a tunnel gap through which the polymer can pass. The electrodes are functionalized with a reagent attached thereto, and the reagent is capable of forming a transient bond to a polymer unit. When the transient bond forms between the reagent and the unit, a detectable signal is generated and used to analyze the polymer. |
申请公布号 |
CA2773101(A1) |
申请公布日期 |
2011.08.11 |
申请号 |
CA20112773101 |
申请日期 |
2011.01.31 |
申请人 |
ARIZONA BOARD OF REGENTS |
发明人 |
LINDSAY, STUART;CHANG, SHUAI;HE, JIN;ZHANG, PEIMING;HUANG, SHUO |
分类号 |
G01N27/416;C12M1/34;C12Q1/68;G01N27/30;G01N27/447 |
主分类号 |
G01N27/416 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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