HALF-LIFE PROLONGATION OF PROTEINS

摘要

Pharmaceutical preparation comprising: - a pharmaceutical active protein having at least one LRP-binding site and/or at least one HSPG binding site and - at least one ligand binding to the LRP-binding site and/or the HSPG binding site, the at least one ligand being selected from peptides, sugars, nucleic acids and small chemical compounds, said small chemical compounds having a molecular weight of 5 KDa or less.