发明名称 |
NOVEL PROTEIN HAVING FRUCTOSYL VALYL HISTIDINE OXIDASE ACTIVITY, MODIFIED PROTEIN, AND USE OF THE PROTEIN OR THE MODIFIED PROTEIN |
摘要 |
The present invention provides: a protein having a fructosyl amino acid oxidase activity which protein is useful for measurement of a glycosylated protein (particularly, glycosylated hemoglobin); a modified protein thereof; and use of the protein or the modified protein. The protein of the present invention is, for example, a fructosyl valyl histidine oxidase derived from Phaeosphaeria nodorum, the fructosyl valyl histidine oxidase having excellent thermal stability and substrate specificity and also having a small Km value to fructosyl valyl histidine. This allows a glycosylated protein measuring reagent to be stored in a long time and measurement accuracy of the glycosylated protein measuring reagent to be improved.
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申请公布号 |
US2011195444(A1) |
申请公布日期 |
2011.08.11 |
申请号 |
US200913123052 |
申请日期 |
2009.10.06 |
申请人 |
TOYO BOSEKI KABUSHIKI KAISHA;GEKKEIKAN SAKE CO., LTD. |
发明人 |
HIRAO RIE;KITABAYASHI MASAO;NISHIYA YOSHIAKI;ISHIDA HIROKI;HATA YOJI |
分类号 |
C12Q1/26;C07H21/00;C12N5/10;C12N9/02;C12N15/85 |
主分类号 |
C12Q1/26 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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