HETEROCYCLIC COMPOUND HAVING NPY Y5 RECEPTOR ANTAGONISTIC ACTIVITY

摘要

Provided is a compound represented by formula (I), a pharmaceutically acceptable salt thereof, or a solvate thereof as a novel compound having an NPY Y5 receptor antagonistic activity. In formula (I), R1, R2, and R3 each independently represent hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted aryl, or the like, or R1 and R2 may be combined together with the adjacent nitrogen atom to form a substituted or unsubstituted nitrogen-containing aromatic heterocycle or the like; X represents S(O), S(O)2, or C(O); R4 and R5 each independently represent hydrogen or substituted or unsubstituted alkyl, or R4 and R5 may be combined to form oxo; R6 represents hydrogen or substituted or unsubstituted alkyl; R's each independently represent halogen, oxo, substituted or unsubstituted alkyl, or the like; m represents an integer of 0 to 2; Y represents S or O; R7's each independently represent halogen or the like; and n represents an integer of 0 to 2.