| 发明名称 |
SELECTIVE REDUCTION OF ALLELIC VARIANTS |
| 摘要 |
<p>Disclosed herein are antisense compounds and methods for selectively of reducing expression of an allelic variant of a gene containing a single nucleotide polymorphism (SNP). Such methods, compounds, and composition are useful to treat, prevent, or ameliorate diseases, including neurodegenerative, such as Huntington's Disease (HD).</p> |
| 申请公布号 |
CA2789005(A1) |
申请公布日期 |
2011.08.11 |
| 申请号 |
CA20112789005 |
申请日期 |
2011.02.08 |
| 申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
BENNETT, C. FRANK;FREIER, SUSAN M.;GREENLEE, SARAH;SWAYZE, ERIC E. |
| 分类号 |
C12N15/113;A61K31/7088;A61K31/7115;A61K31/712;A61K31/7125;C07H21/00 |
主分类号 |
C12N15/113 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
