发明名称 DLL4-BINGING MOLECULES
摘要 DII4-binding molecules, preferably DII4-binding immunoglobulin single variable domains like VHHs and VHs, pharmaceutical compositions containing same and their use in the treatment of diseases that are associated with DII4-mediated effects on angiogenesis. Bispecific DII4-binding molecules that also bind to VEGF-A. Nucleic acids encoding DII4-binding molecules, host cells and methods for preparing same.
申请公布号 US2011195494(A1) 申请公布日期 2011.08.11
申请号 US20100894947 申请日期 2010.09.30
申请人 BOEHRINGER INGELHEIM INTERNATIONAL GMBH 发明人 BORGES ERIC;GSCHWIND ANDREAS;BOUCNEAU JOACHIM;DE TAVERNIER EVELYN;KOLKMAN JOOST;MERCHIERS PASCAL;VAN HOORICK DIANE
分类号 C07K16/18;C07K7/08;C07K14/00;C12N5/00;C12N15/13 主分类号 C07K16/18
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