发明名称 |
CD9-SPECIFIC HUMAN ANTIBODIES |
摘要 |
The present invention relates to a CD9-specific human antibody, more precisely a CD9-specific human antibody composed of human derived CD9-specific complementarity determining region (CDR) and framework region (FR). The human antibody of the present invention recognizes CD9 extracellular loop 2 domain (CD9-ECL2) as an epitope and thereby strongly binding thereto. The human antibody of the present invention also has CD9 antigen neutralizing effect and at the same time inhibiting effect on tumor cell lines. Therefore, it can be effectively used for the prevention and treatment of cancer overexpressing CD9. |
申请公布号 |
US2011195027(A1) |
申请公布日期 |
2011.08.11 |
申请号 |
US20080523516 |
申请日期 |
2008.11.24 |
申请人 |
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发明人 |
PARK YOUNG WOO;CHOI SO-YOUNG;PARK JI HYUN;YU JUNG;SONG EUN-JUNG;KIM SUNGSUB;JANG MYEOUNG HEE;PARK MI-JU;LEE JE-HO;HWANG JAE RYOUNG |
分类号 |
A61K49/06;A61K39/395;A61K49/00;A61P35/00;C07H21/04;C07K16/28;C12N5/10;C12N15/63;C12P21/06;G01N33/574 |
主分类号 |
A61K49/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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