发明名称 |
PROCESS FOR OBTAINING ANTIBODIES |
摘要 |
The present disclosure relates to a method for the manufacture of recombinant antibody molecules comprising culturing a host cell sample transformed with an expression vector encoding a recombinant antibody molecule; adding an extraction buffer to the sample; and subjecting the sample to a heat treatment step; wherein the pH of the sample is detected after addition of the extraction buffer, and optionally adjusted, to ensure that the pH of the sample is 6 to 9 prior to the heat treatment step.
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申请公布号 |
CA2788967(A1) |
申请公布日期 |
2011.08.11 |
申请号 |
CA20112788967 |
申请日期 |
2011.02.02 |
申请人 |
UCB PHARMA, S.A. |
发明人 |
BILGISCHER, JEAN-PASCAL PIERRE;BASSETT, PHILIP JONATHAN;PEARCE-HIGGINS, MARK ROBERT;KENNY, ANDREW JOHN |
分类号 |
C07K16/00 |
主分类号 |
C07K16/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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