发明名称 Nucleoside analogues and oligonucleotide derivative comprising nucleotide analogue thereof
摘要 <p>Compounds of the following general formula (1) and salts thereof: where A represents a direct bond, an alkylene group having 1 to 4 carbon atoms, etc.; B represents an aromatic heterocyclic group which may have a substituent, etc.; R 1 , R 2 , R 3 and R 4 each represent a hydrogen atom, a protective group for an amino group, a protective group for a hydroxyl group, a phosphate group, or -P(R 7 )R 8 [where R 7 and R 8 each represent a hydroxyl group, a protected hydroxyl group, a mercapto group, a protected mercapto group, etc.]. These compounds are useful as oligonucleotide analogues useful for the antisense method, and as nucleoside analogues for producing their intermediates.</p>
申请公布号 EP2354148(A2) 申请公布日期 2011.08.10
申请号 EP20100011213 申请日期 2003.02.13
申请人 IMANISHI, TAKESHI 发明人 IMANISHI, TAKESHI
分类号 C07H19/16;A61K31/712;A61P31/12;A61P35/00;C07H19/06;C07H19/10;C07H19/20;C07H21/00 主分类号 C07H19/16
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