发明名称 |
Unnatural reactive amino acid genetic code additions |
摘要 |
This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNAsyn-thetases, pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.
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申请公布号 |
US7993872(B2) |
申请公布日期 |
2011.08.09 |
申请号 |
US20040561121 |
申请日期 |
2004.04.16 |
申请人 |
THE SCRIPPS RESEARCH INSTITUTE |
发明人 |
DEITERS ALEXANDER;CROPP T. ASHTON;CHIN JASON W.;ANDERSON J. CHRISTOPHER;SCHULTZ PETER G. |
分类号 |
G01N33/53;C07K14/195;C12N;C12N1/21;C12N9/16;C12P21/06 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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