| 发明名称 |
RNAi modulation of the BCR-ABL fusion gene and uses thereof |
| 摘要 |
The invention relates to compositions and methods for modulating the expression of Bcr-Abl, and more particularly to the down-regulation of Bcr-Abl mRNA and Bcr-Abl protein levels by oligonucleotides via RNA interference, e.g., chemically modified oligonucleotides.
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| 申请公布号 |
US7994307(B2) |
申请公布日期 |
2011.08.09 |
| 申请号 |
US20090510128 |
申请日期 |
2009.07.27 |
| 申请人 |
ALNYLAM PHARMACEUTICALS, INC. |
发明人 |
HADWIGER PHILIPP;VORNLOCHER HANS-PETER;VAN DER KUIP HEIKO |
| 分类号 |
C07H21/04;A61K48/00;C07H21/02 |
主分类号 |
C07H21/04 |
| 代理机构 |
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