发明名称 Small peptides and methods for inhibiting the infiltration of eosinophils into airways
摘要 Methods for treating cutaneous inflammation, are described. Also described is a method for inhibiting the mucous release into airways of a patient, methods for blocking IgE activation and for stabilizing the cell membrane of lymphocytes, mast cells, basophils, macrophages, monocytes, eosinophils, neutrophils, and the like, thereby preventing their further involvement in the increased inflammatory response to an IgE antigen challenge, and a method for inhibiting the migration of T-cells. Such methods involve administering to said patient a therapeutically effective amount of a peptide having the formula f-Met-Leu-X, wherein X is selected from the group consisting of Tyr, Tyr-Phe, Phe-Phe and Phe-Tyr.
申请公布号 US7994137(B2) 申请公布日期 2011.08.09
申请号 US20070942371 申请日期 2007.11.19
申请人 MOWYCAL LENDING, LLC 发明人 HOUCK JOHN C.;CLAGETT JAMES
分类号 A61K38/07;A61K45/00;A61K38/00;A61P11/06;A61P19/02;A61P29/00;A61P37/02;A61P43/00;C07K5/00;C07K5/08;C07K5/083;C07K5/10;C07K5/103;C07K7/06 主分类号 A61K38/07
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