| 发明名称 |
INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-4 PROTEASE |
| 摘要 |
<p>Methods for screening for altered focal proliferation states in non-pregnant patients, which include detecting levels of pregnancy-associated plasma protein-A (PAPP-A), are described. Methods for identifying agents that alter the protease activity of PAPP-A, and pharmaceutical compositions and medical devices that include such agents are also described.</p> |
| 申请公布号 |
CA2367360(C) |
申请公布日期 |
2011.08.09 |
| 申请号 |
CA20002367360 |
申请日期 |
2000.03.15 |
| 申请人 |
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH;COMO HOLDING APS |
发明人 |
OVERGAARD, MICHAEL TOFT;OXVIG, CLAUS;CONOVER, CHERYL A. |
| 分类号 |
A61K39/395;G01N33/50;A61B17/58;A61F2/84;A61K38/00;A61K45/00;A61L31/00;A61P5/24;A61P9/10;A61P17/02;A61P19/10;A61P25/00;A61P35/00;A61P43/00;C07K16/18;C12N9/00;C12N9/64;C12N15/09;C12P21/08;C12Q1/00;C12Q1/37;C12Q1/68;G01N33/53;G01N33/577;G01N33/68 |
主分类号 |
A61K39/395 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
