发明名称 |
Method and probes for the detection of a tumor-specific fusion protein |
摘要 |
The invention relates to the detection of fusion proteins. Described are a set of at least a first and a second molecular probe, each probe provided with a dye wherein the dyes together allow energy transfer, at least one probe provided with a reactive group allowing juxtaposing at least the first and second probes wherein the reactive group allows modulation of juxtaposing the probes such that there is an increased likelihood of energy transfer between the dyes. A method is provided which permits detecting the presence of a fusion protein in a cell at the single cell level.
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申请公布号 |
US7993850(B2) |
申请公布日期 |
2011.08.09 |
申请号 |
US20090462637 |
申请日期 |
2009.08.06 |
申请人 |
ERASMUS UNIVERSITEIT ROTTERDAM |
发明人 |
VAN DONGEN JACOBUS JOHANNES MARIA |
分类号 |
G01N33/533;G01N33/542;G01N33/574 |
主分类号 |
G01N33/533 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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