发明名称 |
CELL, METHOD AND KIT FOR CONDUCTING AN ASSAY FOR NEUTRALIZING ANTIBODIES |
摘要 |
The present invention provides a cell for use in a one-step cell-based assay for an extracellular ligand (e.g., I FNα) that initiates a ligand-specific signal at the nucleus of the cell and for neutralizing antibodies against the extracellular ligand. The cell-based one-step assay allows both the extracellular ligand concentration and the neutralizing antibody titer to be quantified in a single sample (e.g., serum) without the need for sample dilution and addition of exogenous extracellular ligand.
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申请公布号 |
US2011189658(A1) |
申请公布日期 |
2011.08.04 |
申请号 |
US20090921110 |
申请日期 |
2009.03.04 |
申请人 |
LE CENTRE NATIONALE DE LA RECHERCHE SCIENTIFIQUE;BIOMONITOR LIMITED |
发明人 |
TOVEY MICHAEL;LALLEMAND CHRISTOPHER |
分类号 |
C12Q1/68;C12M1/34;C12N5/10 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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